Vesicle Fusion 2017-04-02T17:41:32+00:00

Project Description

Vesicle Fusion

How does the synapse maintain high rates of vesicle fusion?

By developing new technology to monitor vesicle fusion in real time, we identified a component of release that requires vesicle trafficking and are now identifying the molecular mechanisms responsible for this release component. Here to we use electrophysiological, pharmacological, genetic and optical tools to delineate mechanisms underlying synaptic vesicle trafficking.