Project Description


Now that we know that fast adaptation is not dependent on calcium entry, what is the mechanism of this process and what is its physiological relevance?

Fast adaptation is a process that modulates the hair cell dynamic range with kinetics measured down to the 10s of microseconds. These rapid kinetics limit potential mechanisms. Although multiple theories exist as to the mechanism of fast adaptation, we are no closer to explicitly understanding either its function or the molecular underpinnings responsible for its manifestation.